What is ARB™ technology?Updated 17 hours ago
Quick answer
ARB™ (Androgen Receptor Blocker) is Adegen's proprietary fatty-acid complex that blocks DHT at the hair follicle, locally, without altering hormone levels in the rest of your body. It's the foundation of every Adegen topical and pairs with two more proprietary systems: DermalDrive™ (a delivery technology) and CryoSafe™ (a no-heat compounding process).
The Full Answer
Most hair loss treatments either ignore DHT or shut it down systemically. ARB™ takes a different approach: it stops DHT from binding to the androgen receptor at the follicle itself, which is where miniaturization actually starts.
Here's how the three technologies work together:
1. ARB™: Stops DHT at the source
ARB™ is a proprietary blend of linoleic and oleic organic fatty acids designed to block DHT from binding to the androgen receptor at the hair follicle. When DHT can't bind, it can't disrupt blood flow at the follicle, and the conditions needed for healthy growth are restored. Because it works locally, only where it's applied, it avoids the systemic hormone effects that come with oral DHT blockers used alone.
2. DermalDrive™: Gets the actives to the follicle
Active ingredients only work if they reach the follicle. DermalDrive™ is Adegen's low-surface-tension delivery system, engineered to carry every active past the skin barrier without crystallizing, separating, or degrading. The result is faster absorption, deeper delivery, and more consistent results from the same ingredients.
3. CryoSafe™: Preserves potency in compounding
Conventional compounding uses heat to blend and stabilize formulas. Heat degrades sensitive actives like tretinoin and reduces potency. CryoSafe™ is our proprietary no-heat process that keeps every ingredient chemically intact from formulation to application, so what's on the label is what reaches your scalp.
How This Compares to Standard Minoxidil
Standard minoxidil increases blood flow to the follicle but does nothing about the DHT signal that restricted that blood flow in the first place. ARB™ addresses the underlying cause; minoxidil supports circulation. Used together inside an Adegen topical, they reinforce each other instead of working in isolation.
Where You'll Find It
ARB™ is in every Adegen topical (A5, A5F, A5D, A15, A15F, A15D) and in ARB™ Shampoo+. The shampoo version is designed to deliver ARB™ actives during cleansing as part of step 1 of the protocol.
Next steps
- If you'd like a treatment recommendation, take the HairIQ™ assessment: it routes you to the variant that fits your situation.
- If you'd like to talk to a person about the science before purchasing, message us and we'll connect you with a team member.